Jeremy Medina
April 17, 2009 AT 04:00 AM EDT

On EW.com’s Music Mix blog, we recently asked you to choose the all-time most wrenching songs. The response was huge: almost 2,000 comments. Here are just a few of your picks. And to see EW’s own list of the top 50, go to music-mix.ew.com/heartbreak.

Bonnie Raitt ”I Can’t Make You Love Me”
Reader Comment: ”She sings it like the man just walked out the door a moment before!” — tom

Radiohead ”Fake Plastic Trees”
Reader Comment: ”If this doesn’t make you emotional, then you have no soul.” — Mike

John Mayer ”Dreaming With a Broken Heart”
Reader Comment: ”I thought it was about someone leaving and the other person having to deal with that. But then I realized it’s about having someone die and having to wake up every day knowing they aren’t there anymore.” — Jenn

George Jones ”He Stopped Loving Her Today”
Reader Comment: ”A guy is faithful to a love not returned, all the way to his death! It doesn’t get sadder!” — Larry

Warren Zevon ”Keep Me in Your Heart”
Reader Comment: ”Nothing is sadder than a dying man with cancer writing his farewell song. Absolutely heart-wrenching lyrics.” — JR

Sinéad O’Connor ”Nothing Compares 2 U”
Reader Comment: ”Maybe it is just because I was in the middle of a breakup when it was popular, but I get choked up when I hear it.” — Jeannie

Eric Clapton ”Tears in Heaven”
Reader Comment: ”As a parent, it brings tears to my eyes and makes me want to hug my kids.” — Sparko

Jeff Buckley ”Hallelujah”
Reader Comment:‘I have yet to listen to it without crying. It’s the combination of a beautiful song, beautifully sung, and knowing what happened to Buckley.” — Miranda

Christina Aguilera ”Hurt”
Reader Comment: ”It really reminds me of my stepdad, who I never got to thank for all the great things he did for me. Ah, here come the tears.” — smn

The Beatles ”Eleanor Rigby”
Reader Comment: ”It searches beyond a broken heart to the profound existential angst of loneliness, a universal experience. It kills me every time.” — jaime47

Johnny Cash ”Hurt”
Reader Comment: ”It was released right before his wife died. He died not long after. I don’t recall anyone being able to listen to that song without ending up a blubbering mess. Brings tears to my eyes just thinking about it.” — Big Don

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