Jennifer Armstrong
August 18, 2009 AT 12:35 PM EDT

James McAvoy and Seth Rogen will headline the Nicole Holofcener-directed screen adaptation of Will Reiser’s humorous novel I’m With Cancer, according to Variety. McAvoy will play a 25-year-old who beats cancer, a character based on screenwriter Reiser’s own experiences. Rogen will costar and produce; Reiser wrote the script as well, which will begin shooting in January.

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