Michael Ausiello and Andy Patrick
July 02, 2010 AT 04:30 PM EDT

Image Credit: Kevin Perkins/Gaz Shirley/PacificCoastNews.comHard as it is to imagine, next season on House, Doc Crankypants may be—gasp!—happy. At least happy-ish. In fact, in the premiere, we’ll see him smiling, laughing, and canoodling on the beach with at-long-last ladylove Cuddy. Clearly this can mean only one thing: The relationship is doomed, right? “I don’t think [so], necessarily,” Hugh Laurie tells me. “But let’s face it, neither of these characters has a clean license.

“‘Buckle up,'” he adds, “would be my advice.”

Lisa Edelstein, who plays House’s significant other, shares her costar’s trepidation. “I was terrified of saying ‘I love you,'” she admits. “But I think that in the final scene of season 6, Cuddy makes it clear that she’s ready to go for it.”

Laurie is ready too, weird as it may feel to him. “Even the appearance of happiness [in House] has taken some getting used to,” he says. “I had a week of happiness training before the season started up, and I’m whistling more than usual.”

Is his small-screen counterpart whistling more than he did, say, when he was with Sela Ward’s Stacy? “I’ve always thought of House as a romantic, and I don’t think romantics are much given to comparing,” Laurie demurs. “But speaking as a friend of House, he seems to be attracted to strong women. He likes to get as good as he gives—and I mean that in as many senses as are suitable for a family readership.”

Your thoughts? Can Huddy make it work? Or is the beginning of their romance the end of House as we know (and love) it? Sound off below!

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