Reed Saxon/AP Images
Jeff Labrecque
November 14, 2011 AT 06:50 PM EST

Neil Patrick Harris will co-host Live! with Kelly for five shows, beginning Nov. 28, the show announced today. Harris, who currently is starring in A Very Harold and Kumar 3D Christmas, has filled in for Regis Philbin in the past. Among the guests sitting down with Harris and Ripa will be Betty White, Maya Rudolph, Marcia Cross, supermodel Molly Sims, Angie Harmon, and Kristen Johnston. The week also will feature musical performances by Avril Lavigne, Hot Chelle Rae and Cobra Starship, plus a special demo by Science Bob.

Jerry Seinfeld will guest-host on Nov. 21-23.

Read more:

Regis and Kelly: Our Favorite Memories

Regis Philbin says contract squabbles pushed him out at ‘Live!’, eyes return to primetime

Regis Philbin leaving ‘Live! with Regis & Kelly.’ Who should fill his seat?

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