Hillary Busis
October 05, 2013 AT 03:04 PM EDT

Roseanne Barr is at it again.

Here, “it” refers to a long, vitriolic Twitter rant directed at someone from the comedian’s past. Back in July, ex-husband Tom Arnold was the focus of Roseanne’s wrath. Yesterday, she turned to a trifecta of targets: Ashton Kutcher, Two and a Half Men, and Chuck Lorre, the CBS sitcom’s creator — who got his big break when he was hired as a supervising producer on Barr’s ’90s hit Roseanne.

On Friday, Barr discovered that Thursday’s episode of Men featured Kutcher delivering a raunchy joke about being 91 years old: “I’d imagine that you’re wet in the places you used to be dry, and dry in the places you used to be wet.” The line is similar to one Barr has been telling since at least 2006, though in her case, it refers to the effects of menopause: “I’m wet where I’m supposed to be dry and dry where I’m supposed to be wet.”

Barr ripped into the actor, the show, and Lorre on Twitter: “i would steal one of his jokes to make it even,” she wrote, “but they all suck ass.”

Though Kutcher, Lorre, and CBS didn’t responded to Barr’s complaints, the comedian did eventually dial things back — calling Lorre one of her “two most successful interns” (along with Joss Whedon, who wrote for Roseanne in 1989) and eventually tweeting, “I forgive Ashton and Chuck! It’s prob one of their writer’s fault!”

See Barr’s expletive-filled rant below. (NSFW language obviously follows.)

CBS has not responded to EW’s request for comment.

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