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Ariana Bacle
November 02, 2014 AT 07:39 PM EST

Hollywood’s strangest duo is at it again: Johnny Depp appeared onstage at a Marilyn Manson show Friday night to play guitar.

Depp and Manson shared the stage back in 2012 at the Revolver Golden Gods Awards, where they played a cover of Eurythmics’ “Sweet Dreams (Are Made of This).” Soon after, they collaborated again for a cover of Carly Simon’s “You’re So Vain” that appeared as a bonus track on Manson’s 2012 album, Born Villain. 

For Manson’s Halloween show, Depp jumped onstage to play guitar for “The Beautiful People” while Manson sang lead vocals. Watch a clip of the performance over at the Daily Mail.

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