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Samantha Highfill
May 18, 2015 AT 07:22 PM EDT

T.R. Knight, best known for playing George O’Malley on five seasons of Grey’s Anatomy, is returning to TV with Hulu’s original event series 11/22/63

Based on Stephen King’s novel, 11/22/63 follows Jake Epping (James Franco), a divorced English teacher who tries to prevent the assassination of President Kennedy. Along the way, Jake’s mission is threatened by many factors, including love, Lee Harvey Oswald, and the very fact that the past does not want to be changed.

Knight will play Johnny Clayton, a salesman in 1960s Texas whose wife, Sadie Dunhill (Sarah Gadon), falls in love with Jake. Let’s just say that Johnny and Jake have a confrontation—and that Johnny has a few secrets of his own.     

The 11/22/63 cast also includes Chris Cooper and Cherry Jones.

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