Oliver Gettell
April 06, 2016 AT 12:00 PM EDT

Ellen DeGeneres has spoken out about the controversial “religious freedom” bill passed in Mississippi this week, calling it “the definition of discrimination.”

The legislation signed by Gov. Phil Bryant on Tuesday says the state government will not punish individuals, religious organizations, or certain business for refusing to provide services to people because of a religious opposition to same-sex marriage, extramarital sex, or transgender people.

In a video preview of her Thursday monologue on The Ellen DeGeneres Show, the openly gay host framed the issue as one of human rights, not politics.

“It’s also something that the Supreme Court already ruled on when they made marriage a right for everyone, everyone,” DeGeneres said. “And they’re Supreme. I mean, that’s the best you can get. Like the Nacho Supreme from Taco Bell.”

By turns humorous and heartfelt, she added that she grew up in the South, in Louisiana. “If you’re in Mississippi or North Carolina or anywhere and you’re saddened by the fact that people are judging you based on who you love, don’t lose hope,” she said. “I was fired for being gay, and I know what it feels like. I lost everything. But look at me now. I could buy that governor’s mansion, flip it, and make a $7 million dollar profit.”

DeGeneres wrapped up by calling for “less hate and more love.”

Watch her monologue above.

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