Karwai Tang/WireImage; Michael Bezjian/Getty Images
Danielle Jackson
September 27, 2016 AT 04:29 PM EDT

Don’t mess with Madonna’s friends.

Following Monday night’s presidential debate, where Donald Trump made yet another derogatory remark about Rosie O’Donnell, Madonna defended the comedian via social media. The singer uploaded a screen grab of herself and O’Donnell from A League of Their Own with the caption, “Mess with my girl Rosie and you’re messing with me!!! Cruelty never made anyone a winner. #rebelhearts4ever.”

O’Donnell also tweeted about Trump on Monday night, referring to him as an “orange anus” and sharing the video in which their infamous feud was born. 

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