Romance goes high-concept with this dramedy: A directionless woman (Jennifer Aniston), unsure if she wants to marry her fiancé (Mark Ruffalo), heads West to attend her sister's wedding, only to discover that random plot twist alert! her family was the inspiration for the film The Graduate. ''It's got all this stuff about The Graduate, but at the core it's a journey into self-discovery, and what this woman has to go through to give herself over to somebody in a meaningful way,'' says Rob Reiner, who replaced original director T.M. Griffin because of creative differences. ''If [audiences] are expecting a sequel to The Graduate, then they're going to be disappointed,'' adds Reiner. ''But if you're going to see a good romantic comedy with a different premise than you've seen before, then it is a good story.''