There's a long line of recurring characters who've nettled, unsettled, or otherwise tried to destroy the choleric doc. Who's come closest to making House's blood truly boil?
Seasons 1, 2
The hottie ex-girlfriend drove House nuts as she batted her lashes while begging the understandably frustrated doc to save her sick husband. Temperature: 140 degrees
As a vengeful cop, Morse didn't take kindly to a rude encounter with House so he aimed to toss the doc behind bars, while fiercely targeting everyone he knew. Temperature: 210 degrees
House dubbed the job seeker ''Cutthroat Bitch,'' but she was a bigger threat to him as Wilson's squeeze. The trio were forced to hammer out a custody agreement for Wilson's time. Temperature: 170 degrees
House uses PI Douglas as his surrogate pushy jerk and reluctant fill-in friend, making the pro snoop the only visitor who might actually be welcomed back. Temperature: 100 degrees