Morgan Fairchild]
Roseanne (1992)
The cherry on top of Sandra Bernhard's beloved, unabashed Nancy? Her
glam girlfriend Marla (Fairchild).
Winona Ryder
Friends (2001)
What was ''the one wild thing'' Rachel (Jennifer Aniston) ever did? Smooch
old friend Melissa (Ryder).
Edie Falco
Will & Grace (2004)
Falco and Chloë Sevigny made such a powerful lesbian couple that they
had Grace (Debra Messing) questioning her sexuality.
Olivia Wilde
The O.C. (2004-05)
The introduction of Alex (Wilde) — who locked lips with Marissa (Mischa
Barton) — was a pivotal, shark-jumping moment for the teen soap.
Swoosie Kurtz
Desperate Housewives (2009)
Susan (Teri Hatcher) has perpetual man troubles, but her love life took
an even sharper turn when co-worker Kurtz hit on her.
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