Thorne-Smith I got the call from David E. Kelley to do Ally McBeal; it came really quickly after Melrose. That was a once-in-a-lifetime thing.
Show It was the seminal job of my career. There is BMP Before Melrose Place and AMP. To this day I'm still working because of that show.
Zuniga I just feel so fortunate that I got to be on a show that made a lot of people happy.
Shue I got to meet Yitzhak Rabin [at a private event hosted by David Geffen]. I was the only TV person among film actors like Clint Eastwood, Warren Beatty, Barbra Streisand, Richard Dreyfuss. Security comes over and says, ''Mrs. Rabin would like to meet you.'' I go over, and Yitzhak says, ''I remember you on TV, but I don't remember this.'' I had a goatee, and he was touching my chin! I remember Dreyfuss looking at Streisand like, ''Who is this guy?'' Ah, the power of TV.
Leighton My life went from 0 to 60 because of this hugely popular show. I was on the covers of magazines and I was able to buy my first car with air-conditioning.
Locklear I got Spin City from that. And all the perks that came with celebrity! Getting into movies, packed restaurants where miraculously two spots would be available. I'd think, ''Who did we just kick out?'' And getting the front-of-line spots at Disneyland.
Bissett It gave me a name in TV. I am living in Seattle and raising my kid there, but I am able to continue working. Without Melrose, I wouldn't be where I'm at now.
Savant I did receive a lot of business cards from men! And it wasn't until the bitter end of the show when both of us were out of relationships that I noticed Laura. It was like being hit over the head with a sledgehammer. [The two married in 1998.]
Cross It gave me a job at a time when I was really going through something very painful. [Cross' longtime partner Richard Jordan died of a brain tumor in 1993.] That's the reason I was crazy on the show. I was feeling crazy. It was a wonderful place to let it all out.
Update: The Melrose Place CastAndrew Shue
In the years since he left Melrose, Shue, 45, has cofounded the nonprofit organization Do Some-thing and now works on the social-networking website CafeMom, which he cofounded.Laura Leighton
The 44-year-old actress currently plays Ashley Marin on ABC Family's hit teen soap Pretty Little Liars.Courtney Thorne-Smith
Thorne-Smith, 44, went on to star on Ally McBeal and According to Jim, and now recurs as Lyndsey McElroy, Jon Cryer's girlfriend, on CBS' Two and a Half Men.Grant Show
Show, 50, has continued to work regularly in TV, on shows like Swingtown, Private Practice, and Big Love. He'll next star on Marc Cherry's new dramedy, Devious Maids, for Lifetime.Marcia Cross
The 50-year-old actress, who just wrapped an eight-year run as Bree Walker on ABC's Desperate Housewives, is focusing on her children and her charity work.Josie Bissett
Bissett, 42, plays Kathleen on the ABC Family drama The Secret Life of the American Teenager.Daphne Zuniga
After leaving the complex, Zuniga, 49, recurred on series including American Dreams, starred on ABC Family's Beautiful People, and played Victoria Davis for five seasons on The CW's One Tree Hill.Doug Savant
Like his two-time costar Cross, the 48-year-old Savant recently ended an eight-year run on Desperate Housewives, where he played put-upon husband Tom Scavo.Heather Locklear
The beloved blonde went on to join Michael J. Fox on Spin City and later reprised her role as Amanda on The CW's short-lived Melrose Place reboot. Locklear, 51, is currently shooting Scary Movie 5.