A star-studded ''downtown'' cast (Christopher Walken, Dennis Hopper, John Turturro, Rosanna Arquette) can't save this strained satire about getting ahead in the '90s. Griffin Dunne is hyperactive as a low-rent entrepreneur who decides to produce a movie, and the rest of the actors, playing his various business associates, are even more wired. The result is a series of irritating arguments that play like acting exercises. It's a relief when people start shooting each other. Search and Destroy had a meager art-house release but may be worth a rental to see Walken's song and dance in a Japanese-style nightclub about halfway through. After that, hit rewind.