62. JOHNNY DEPP
Ed Wood (1994)

It's just the sort of role that most actors would vamp-and-camp to the extreme: Ed Wood, the cross-dressing, schlock-serving '50s filmmaker/punchline who was at his most comfortable wearing heels. But as the cult ringleader, an admirably restrained Depp is wide-eyed and wistful — the anchor of naive ambition in a sea of kitsch. It's the most well-adjusted weirdo of his career.