4. THE GOSSIP GIRLS
Every generation gets its own pair of pop culture best frenemies, whose tumultuous relationship keeps us coming back for more. Betty and Veronica. Alexis and Krystle. Brenda and Kelly. Ladies, please welcome Gossip Girl's Serena (Blake Lively) and Blair (Leighton Meester) to your vaunted ranks. Whether smacking the Chanel out of each other during a trip to Yale or loyally banding together in Serena's ''I killed someone!'' hour of need, this roller-coaster friendship has provided hours of pure, unadulterated pleasure. Plus, S. and B. totally have the best hair on television. —Tim Stack
