12. DAVID CROSS
All conversations about his genius start here: Along with Bob Odenkirk, he created the cunning HBO sketch series Mr. Show, which routinely put SNL to silly shame. And not only does Cross work little miracles in supporting roles (remember his role as feckless freak-job Tobias on Fox's Arrested Development?), he can drop some pretty fearsome stand-up (who else talks about being raped by the Virgin Mary?). Simply put, this dude never kowtows for his funny.
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