21. DEMETRI MARTIN
You know what's funny? Palindromes and anagrams. ''Shut up, Grandma,'' you say, but we say shut up yourself and watch Demetri Martin work a stand-up mic. ''A drunk driver's very dangerous. Everybody knows that. But so is a drunk backseat driver — if he's persuasive.'' The floppy-haired heir to Steven Wright won a prestigious award at 2007's Edinburgh Festival Fringe, which helped launch him from the comedy underground to a hit show on Comedy Central called Important Things With Demetri Martin.
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