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Contagion

Starring Matt Damon, Kate Winslet, Jude Law, Gwyneth Paltrow  
Directed by Steven Soderbergh, PG-13

Steven Soderbergh knows that his new thriller, Contagion — about a highly communicable virus that wipes out millions of people worldwide in a matter of weeks — may be even more unsettling than most horror films. ''You can avoid going into the ocean or taking a shower if Jaws and Psycho scare the s--- out of you,'' says the director. ''You can't live a normal life without coming into contact with germs.''

Contagion is a kind of Towering Inferno for the science-geek set, featuring an A-list cast whose lives collide amid the ensuing international chaos: Matt Damon plays a Midwestern dad whose wife (Gwyneth Paltrow) is one of the disease's first victims; Kate Winslet appears as a Centers for Disease Control doctor; Marion Cotillard portrays a World Health Organization official; and Jude Law is a crusading blogger. (Sept. 9) —Dave Karger

To find out more about Contagion, pick up this week's issue of Entertainment Weekly.

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Image Credit: Claudette Barius