After a game-changingly merciless freshman season that netted 17 Emmy nods, co-creators Ryan Murphy and Brad Falchuk have packed up L.A.'s Murder House and relocated the series to Briarcliff, a Massachusetts mental institution. Though Asylum, which is largely set in 1964, introduces a whole new crop of characters, one of the most anticipated returning players is Lange. After scoring a Golden Globe for her portrayal of Constance Langdon in season 1, Lange now takes on Sister Jude, a nun who's more sadistic than saintly.