Jojo Whilden/HBO
April 04, 2014 at 01:00 PM EDT

Ryan Murphy, the co-creator of Glee and American Horror Story, tackles his most dramatic and emotional project to date with his adaptation of Larry Kramer’s iconic play The Normal Heart. Set to air May 25 on HBO, the film chronicles the rise of AIDS in New York City in the early 1980s and features a sterling cast, including Mark Ruffalo, Julia Roberts, Matt Bomer, Taylor Kitsch, and Jim Parsons. EW is exclusively premiering Heart‘s new trailer. Watch below.

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